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The Sweet Success of Fenuplex
The Inside Scoop on a Supplement for a Leaner, Healthier You
by Charles Poliquin
8/24/2010 11:45:39 AM
Imagine a pill that could add 2, 5, maybe even 15 years to your life. A Fountain of Youth in a single capsule, if you will. And what if this pill could also help with fat loss? Got your attention? Then let me tell you about one extremely powerful supplement – Fenuplex.
Fenuplex is one of my best-selling products – and with good reason. Its combination of three ingredients – fenugreek, bitter gourd and Gymnema sylvestre – helps deal with the damage done by insulin. Due to poor dietary habits and overeating, many people are producing too much insulin, which damages the pancreas. In fact, our lifestyle is such that it’s estimated that of American children born today, one out of every three will become diabetic. The ingredients in Fenuplex help restore cell function in the pancreas and manage your glucose levels, which is especially important for losing bodyfat.
Five hormones raise blood sugar, but only one lowers sugar: insulin. That is because we are designed to consume a natural diet – not the typical American diet that is disguised as food. One of the basic tenets of the Biosignature system is that modulating insulin will always improve your body composition scores, whether the problem is due to problems in androgen, estrogen or growth hormone. Fenuplex is so effective in dealing with insulin levels that one of my pro hockey clients can attribute a $4 million salary increase to using Fenuplex. Seriously.
When this athlete came to see me, his bodyfat level was 20.5 percent, a bodyfat percentage that high will adversely affective speed and endurance on the ice. In fact, his performance had suffered to the point that his team had threatened him with a $3.5 million salary cut. After just one month of using Fenuplex, his bodyfat dropped to 11.1 percent, and the result was a $4 million salary increase! It was a good investment, as a month later his bodyfat decreased to just six percent and he was performing even better. His physical transformation was such that his teammates teased him at workouts, pretending not to recognize him. But Fenuplex does much more than just help you lose weight and perform better in athletics – it can, in a sense, slow the aging process.
I can say this because having diabetes is known to accelerate aging by 15 years, and for the first time in the history of America it’s probable that the average child born today will not live as long as their parents.
Maintaining healthy blood glucose homeostasis is therefore critical for preserving the health of your clients and minimizing the risk of associated pathological disease.

Over 20 million Americans have to take
daily shots of insulin to control their diabetes.
The higher your glucose levels, the greater your risk
of developing this disease.
What many fail to realize is that insulin resistance takes place in different tissues at different rates. For example, the ovaries become insulin resistant before the muscles do, which means a woman could develop an endocrine disorder called Polycystic Ovary Syndrome (PCOS) before she would get fat.
The Fenuplex Solution
In recent years, many leading universities have researched several plant extracts for their antidiabetic properties in an effort to discover alternative treatment modalities that pose a lower threat for diabetics.A host of herbs are reported to possess some degree of antidiabetic activity, the most well-known being American ginseng. But a significant amount of research, as well as traditional usage, demonstrates that the best choices in dealing with this issue in terms of efficacy and safety are fenugreek seeds, bitter gourd fruit, and gurmar leaf. Also, it is plausible that the insulin and glucose normalizing effects of some of these herbs may benefit non-diabetics who want to improve their insulin sensitivity. Let’s look at these three products in greater detail.
Fenugreek. The use of fenugreek seeds (Trigonella foenum graecum) for the treatment of diabetes has long been described in the Greek and Latin pharmacopoeias. In the recent past, several studies have demonstrated hypoglycemic properties of fenugreek seeds in both animal and human studies, thus lending support to the traditional use of fenugreek.
Research further suggests that fenugreek has a lowering effect on plasma cholesterol and triglyceride levels. The hypoglycemic effect of fenugreek is believed to be largely due to its high soluble-fiber content, which acts to decrease the rate of gastric emptying, thereby delaying the absorption of glucose from the small intestine. Another possible mechanism for the efficacy of fenugreek is its content of a specific amino acid, 4-hydroxyisoleucine, which represents 80 percent of the free amino acids in fenugreek seeds and may possess insulin-stimulating properties.
Fenugreek is also contains compounds with reported hypoglycemic properties, such as trigonelline and coumarin. In the pharmacopoeia compendium of France, you will find fenugreek described as an anabolic agent on the same pages as the androgens Nilevar and Halotestin.
Bitter gourd. Bitter gourd (Momordica charantia), also known as bitter melon and balsam pear, is a tropical vegetable widely cultivated in parts of Asia, Africa and South America. Our expert nutritionist, Jonny Bowden, ranks it highly on any nutritional plan.
It has been extensively used in folk medicine as a remedy for diabetes. Although the precise mechanism of action remains to be fully determined, preliminary evidence suggests that bitter gourd may help to stimulate insulin release or possibly glycogen synthesis in the liver. Further, the plant is believed to contain several antidiabetic compounds. For instance, an insulin-like protein, known as insulin-P or polypeptide-P, has been extracted from M. charantia fruit and has demonstrated hypoglycemic effects when injected subcutaneously into type I diabetics.
Bitter gourd also contains charantin, a mixed steroid compound isolated through alcohol extraction, which was found to be a more potent hypoglycemic agent than tolbutamide.
Gymnema sylvestre. Gymnema sylvestre is an herb that has a long history of use in India for controlling diabetes. Its more common name, gurmar (meaning “sugar-destroying”), was given to it because of the plant’s antisacharogenic property (suppresses the taste of sugar).
Gymnema sylvestre is recommended for improving insulin sensitivity and has the following properties:
* Insulin sensitizing action by increasing activity of enzymes responsible for glucose uptake and utilization
* Assists regeneration and repair of pancreatic beta cells
* Inhibits glucose uptake from the small intestine
* Lowers cholesterol levels
Getting Started
Typically, two capsules of Fenuplex are taken with meals three times a day by clients who show an insulin-type Biosignature. Lean individuals use the Fenuplex at a dose of three capsules when they take their high-carb/protein post-workout shakes. Specifically, these are the dosages of the three ingredients you’ll find in two capsules of Fenuplex:
Fenugreek Seed
6.5:1 Extract (Trigonella foenum-graceum) in 1000 mg (containing a minimum of 70% [700 mg] soluble fiber)
Bitter Gourd Fruit
10:1 Extract (Momordica charantia) in 152 mg (containing bitter principles)
Gymnema Leaf
10:1 Extract (Gymnema sylvestre) in100 mg (standardized to 25% [25 mg] gymnemic acid)
Fenuplex will help you and your clients to achieve the balanced hormone levels described in our Biosignature seminars. It’s great for fat loss, improving athletic performance, and as a supplement that can actually help you live healthier and longer. You might say it’s the closest thing we have to a Fountain of Youth.
Fenuplex is also available for purchase in our EU store!
(Always consult your physician before taking any dietary supplements if you have an existing medical condition; are taking medication; are pregnant or nursing, or if you may become pregnant; and/or if your health status is unknown.)
References:
Marles FJ, Farnsworth NR. Antidiabetic plants and their active constituents: an update. Protocol J Nat Med Winter 1996:85-111.
Nadkarni AK. Indian Materia Medica Popular Prakashan Private Ltd: Bombay, 1976.
Shanmugasundaram KR, et al. Enzyme changes and glucose utilization in diabetic rabbits: the effect of Gymnema sylvestre, R.Br. J Ethnopharmacol 1983;7:205-234.
Shanmugasundaram ERB, et al. Possible regeneration of the islets of langerhans in streptozotocin-diabetic rats given Gymnema sylvestre leaf extracts. J Ethnopharmacol 1990;30:265-279.
Baskaran K, et al. Antidiabetic effect of a leaf extracts form Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-305.
Shanmugasundaram ERB, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-294.
Ali L, et al. Characterization of the hypoglycemic effects of Trigonella foenum graecum seed. Planta Med 1995;61:358-360.
Marles FJ, Farnsworth NR. Antidiabetic plants and their active constituents: an update. Protocol J Nat Med Winter 1996:85-111.
Ribes G, et al. Antidiabetic effects of subractions from fenugreek seeds in diabetic dogs. Proceedings Soc Exper Biol Med 1986;182:159-166.
Ajabnoor MA, Tilmisany AK. Effect of Trigonella foenum graecum on blood glucose levels in normal and alloxan-diabetic mice. J Ethnopharmacol 1988;22:45-49.
Khosla P, et al. Effect of Trigonella foenum graecum (fenugreek) on blood glucose in normal and diabetic rats. Indian J Physiol Pharmacol 1995;39:173-174.
Bordia A, et al. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenum graecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prost Leuko EFA1997;56:379-384.
Haefele C. et al. Characterization of a dioxygenase from Trigonella foenum graecum involved in 4-hydroxyisoleucine biosynthesis. Phytochem 1997;44:563-566.
Sharma RD, et al. Effect of fenugreek seeds on blood glucose and serum lipids in Type I diabetes. Eur J Clin Nutr 1990;44:301-306.
Sharma RD. Effect of fenugreek seeds and leaves on blood glucose and serum insulin responses in human subjects. Nutr Res 1986;6:1353-1364.
Madar Z, et al. Glucose-lowering effect of fenugreek in non-insulin dependent diabetics. Eur J Clin Nutr 1988;42:51-54
Welihinda J, et al. The insulin-releasing activity of the tropical plant Momordica charantia. Acta Biol Med Germ 1982;41:1229-1240.
Karunanayake EH, et al. Effect of Momordica charantia fruit juice on streptozotocin-induced diabetes in rats. J Ethnopharmacol 1990;30:199-204.
Singh N, et al. Effects of long term feeding of acetone extract of Momordica charantia (whole fruit powder) on alloxan diabetic albino rats. Ind J Physiol Pharmac 1989;33:97-100.
Ali L, et al. Studies on hypoglycemic effects of fruit pulp, seed, and whole plant of Momordia charantia on normal and diabetic model rats. Planta Med 1993;59:408-411.
Srivastava Y, et al. Effect of Momordica charantia Linn. Pomous aqueous extract on cataractogenesis in murine alloxan diabetics. Pharmacol Res Comm 1988;20:201-209.
Srivastava Y, et al. Antidiabetic and adaptogenic properties of Momordica charantia extract: an experimental and clinical evaluation. Phytotherapy Res 1993;7:285-289.
Welihinda J. et al. Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes. J Ethnopharmacol 1986;17:277-282.
Leatherdale BA, et al. Improvement in glucose tolerance due to Momordia charantia (Karela). Br Med J 1981;282:1823-1824.
NG TB, et al. Insulin-like molecules in Momordica charantia seeds. J Ethnopharmacol 1986;15:107-117.
Sheela CG, Augusti KT. Antidiabetic effects of S-allyl cysteine sulphoxide isolated form garlic Allium sativum Linn. Ind J Exper Biol 1992;30:523-526.
Sharma KK et al. Antihyperglycemic effect on onion: effect on fasting blood sugar and induced hyperglycemia in man. Ind J Med Res 1977;65:422-429.
Brown D. Encyclopedia of Herbs and Their Uses. Dorling Kindersley: New York, 1995.
Hikino H et al. Isolation and hypoglycemic activity of trichosans A, B, C, D, and E: glycans of Trichosanthes kirilowii roots. Planta Med 1989;55:349-350.
Miura T et al. Antidiabetic effect of seishin-knaro-to in KK-Ay mice. Planta Med 1997;63:320-322.
Yeung, H. Handbook of Chinese Herbs and Formulas, vol. 1, Institute of Chinese Medicine: California, 1983, pages 529-530, 475, 504, 378-79, 223-225, 214.
Miura, T. et al, Hypoglycemic activity of To-Kai-San (Chinese medicines) in normal and KK-Ay mice. J. Nutr. Sci Vitaminol. 1997;43:11-17
Valette G, et al. Hypocholesterolemic effect of fenugreek seeds in dogs. Atherosclerosis 1984;50:105-111.
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